Which statement about the risk and Pap smear schedule in HPV-related genital infections is correct?

• A. Having condylomata acuminata elevates cervical cancer risk, so annual Pap smears are advised.
• B. HPV cannot be transmitted orally.
• C. Condoms guarantee complete prevention of HPV transmission.
• D. Metronidazole is the treatment of choice for condylomata acuminata.

Answer: (A)

The main idea is that HPV infection is the key driver of cervical cancer risk, and signs of HPV infection like condylomata acuminata flag the need for cervical cancer screening. Having genital warts indicates HPV exposure, and cervical cancer risk is linked to persistent infection with high‑risk HPV types. Because of that risk, regular cervical screening has historically been recommended to detect precancerous changes early, with annual Pap smears described in this context.

HPV can be transmitted through oral-genital contact, so the statement that it cannot be transmitted orally is incorrect. Condoms reduce the risk of HPV transmission but do not guarantee complete protection, since HPV can infect skin in areas not covered by a condom. Metronidazole targets bacterial and protozoal infections (like bacterial vaginosis or trichomoniasis) and is not a treatment for condylomata acuminata, which are caused by HPV lesions.