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Multiple Choice

Which of the following is a contraindication to renal transplantation?

Active infection is a contraindication to renal transplantation because the immunosuppressive drugs required after transplant would let the infection worsen, potentially leading to sepsis and failure of the graft or the patient. Before transplantation, infections must be treated and cleared, and the patient re-evaluated to ensure there is no active infection. Good nutritional status and absence of active cancer are favorable factors for transplantation, while severe comorbidity with poor prognosis can also preclude it, but the presence of an active infection is the clearest, immediate reason to withhold transplantation until it is resolved.

Active infection is a contraindication to renal transplantation because the immunosuppressive drugs required after transplant would let the infection worsen, potentially leading to sepsis and failure of the graft or the patient. Before transplantation, infections must be treated and cleared, and the patient re-evaluated to ensure there is no active infection.

Good nutritional status and absence of active cancer are favorable factors for transplantation, while severe comorbidity with poor prognosis can also preclude it, but the presence of an active infection is the clearest, immediate reason to withhold transplantation until it is resolved.