What effect does RAAS activation have on the kidney, and how do ACE inhibitors alter this?

• A. RAAS activation increases glomerular pressure and promotes fibrosis; ACE inhibitors reduce proteinuria and slow progression.
• B. RAAS activation decreases glomerular pressure; ACE inhibitors worsen progression.
• C. ACE inhibitors have no effect on proteinuria.
• D. RAAS activation reduces fibrosis; ACE inhibitors increase proteinuria.

Answer: (A)