To monitor CKD progression in diabetics, clinicians commonly use:

• A. Blood glucose
• B. Serum potassium
• C. eGFR and urinary albumin-to-creatinine ratio
• D. Urine osmolality

Answer: (C)

Tracking kidney function over time is essential to gauge CKD progression. The most informative combination is the estimated glomerular filtration rate, which shows how well the kidneys are filtering, together with the urinary albumin-to-creatinine ratio, which reveals how much protein is leaking due to glomerular damage. In diabetics, albuminuria can appear early and correlates with risk of decline, so using both measures provides a fuller picture of progression, helps estimate prognosis, and guides treatment to slow damage. Blood glucose reflects diabetes control but doesn’t quantify CKD progression itself. Serum potassium and urine osmolality are less directly tied to tracking progression over time.